Cyclobenzaprine: Generic, Uses, Side Effects, Dosages, Interactions & Warnings

It blocks the pathway of neurotransmitters that are responsible for the sensation of pain. It relaxes only the muscles and not the actual causative nerves behind the pain. For best results, doctors recommend combining the use of Flexeril with rest and physical therapy. Although rare, deaths may occur from overdosage with FLEXERIL. Multiple drug ingestion (including alcohol) is common in deliberate cyclobenzaprine overdose.

U.S. Prescription Opioid Use Fell 7.4% in 2022 – Pain News Network

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Do not use Flexeril if you have taken an MAO inhibitor in the past 14 days. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. Blurred vision; dizziness; drowsiness; dry mouth; weight gain. A long-acting formulation of cyclobenzaprine has been introduced and is believed by some clinicians to have a lower side effect profile than the immediate-release formulation of this drug.

Symptoms of overdose may include the following:

Serotonin is a neurotransmitter chemical that helps carry pain signals to the brain (4). By preventing serotonin transmission, cyclobenzaprine alleviates pain by reducing the number of pain signals that reach the central nervous system. Flexeril is the brand name for a muscle relaxant called cyclobenzaprine (1). Other brands of cyclobenzaprine include Fexmid, FusePaq Tabradol, and Amrix (an extended-release capsule). Cyclobenzaprine relaxes muscles by reducing muscle spasms. Cyclobenzaprine is a skeletal muscle relaxant that works on the brainstem to treat muscle spasms of local origin.

• When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below.
• Using Flexeril with other drugs that make you drowsy can worsen this effect.
• Flexeril and Diazepam are both used to treat muscle spasms.
• The plasma concentration of cyclobenzaprine is increased in patients with hepatic impairment (see CLINICAL PHARMACOLOGY, Pharmacokinetics, Hepatic Impairment).
• Flexeril withdrawal symptoms can include headache, nausea, fatigue, and cravings for the drug.

Chiropractic care, another form of manual therapy, aligns the spine through spinal manipulation. It demonstrates similar therapeutic effects to physical therapy for neck pain (26). However, physical therapy tends to outperform chiropractic care in the cases of back pain and knee pain. If you take too muchFlexeril, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Drowsiness, dizziness, dry mouth, constipation, or tiredness may occur.

Cyclobenzaprine, oral tablet

Prescription muscle relaxers can be effective in treating spasticity, muscle spasms and muscle-related pain. But it’s important to weigh the possible risks of these medications, flexeril allergic reaction including their side effects and addiction potential. Be sure to talk to your healthcare provider about all the options available to treat your symptoms.

Follow your doctor’s dosing instructions very carefully. Avoid driving or hazardous activity until you know how this medicine will affect you. There are other drugs available to treat your condition. Talk with your doctor about other drug options that may work for you.

As management of overdose is complex and changing, it is recommended that the physician contact a poison control center for current information on treatment. Signs and symptoms of toxicity may develop rapidly after cyclobenzaprine overdose; therefore, hospital monitoring is required as soon as possible. The acute oral LD50 of FLEXERIL is approximately 338 and 425 mg/kg in mice and rats, respectively. Cyclobenzaprine usually begins working about one hour after it is ingested, relaxing muscles and relieving muscle spasms. Formulations include immediate-release and extended-release.

But some OTC medications can help muscle issues (like soreness), such as NSAIDs (nonsteroidal anti-inflammatory drugs) and acetaminophen. Take your time talking with your doctor about your options and listening to their medical advice. Make sure you feel comfortable with your doctor’s approach and treatment plan. In the case of nerve and muscular problems, anxiety and tension can often increase the pain you’re experiencing. So ask the questions you need to ask and collect the information that’s important to you so that you can feel as relaxed as possible in your doctor’s care. Physical therapy can help with back pain, knee pain, and neck pain.

Cyclobenzaprine did not demonstrate mutagenic activity in the male mouse at dose levels of up to 20 times the human dose. Overdose symptoms may include severe drowsiness, vomiting, fast heartbeats, tremors, agitation, or hallucinations. While the addictiveness of cyclobenzaprine is being debated, anyone exhibiting problematic patterns of substance use can benefit from addiction treatment. This is especially true if someone has been engaging in polydrug use with cyclobenzaprine and other substances.

If you feel that you’re dependent on carisoprodol or diazepam or your prescribed dosage isn’t helping to manage your symptoms, don’t take more than your recommended dosage. Each type of prescription muscle relaxer has different possible side effects. It’s important to talk to your provider or a pharmacist about possible side effects of the specific medication you’re taking or thinking of taking. A few types of antidepressants can be used for nerve pain, including tricyclic antidepressants, which include Amitriptyline (Elavil), Doxepin (Sinequan), and Nortriptyline (Pamelor).